Explore 3D Tissue Environments with Solid Synthetic Scaffold Models
Mimic a broad range of 3D tissue microenvironments using solid synthetic scaffold models. Because synthetic scaffolds are devoid of animal-derived materials, they are free of potential pathogens and other issues found with biologic products.
Polymers are a common choice for generating solid scaffolds of diverse size, structure, and porosity. They can be fabricated using lithography, electrospinning, bioprinting and, in the case of permeable supports, microporous membranes. For studies where endogenous factors are required to more realistically mimic the cellular in vivo environment, they can be combined with extracellular matrices (ECMs) as a coating to create effective complex matrices for 3D cell culture.