Because it exposes one side of the culture to liquid media and surrounds the other with air, Air-liquid Interface (ALI) is ideal for studying respiratory tract epithelial cells, which interact with both liquid and air. ALI systems therefore allow researchers to more accurately mimic in vivo conditions compared to using conventional cell culture models. This makes them ideal to perform mechanistic studies of respiratory epithelial cells as drug permeation barriers; to model respiratory diseases like cystic fibrosis and asthma; to investigate essential dermal processes such as wound healing; and to advance understanding of respiratory epithelium infections including Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). From asthma to COPD, ALI models have been critical in researching respiratory diseases. With the recent outbreak and severity of the COVID-19 virus, this technology is becoming even more critical in the race to understand and treat disease.
Better represent in vivo biology in an in vitro environment with air-liquid interface
Better represent in vivo biology in an in vitro environment with air-liquid interface
Products
Tools for ALI Models
Permeable Supports
Permeable Supports
Learn MoreTranswell Permeable Supports
Transwell permeable supports are backed by extensive citations, protocols, and scientific support—all to help create a cell culture that more closely mimics an in vivo environment.
Falcon Permeable Supports
Non-tissue, culture-treated insert housings prevent uninhibited growth of cells on the insert walls and feature an innovative hanging design that facilitates pipetting and allows for co-culture.
Transwell Permeable Supports
Transwell permeable supports are backed by extensive citations, protocols, and scientific support—all to help create a cell culture that more closely mimics an in vivo environment.
Falcon Permeable Supports
Non-tissue, culture-treated insert housings prevent uninhibited growth of cells on the insert walls and feature an innovative hanging design that facilitates pipetting and allows for co-culture.
Resources
Featured Resources
Featured Stories
Ask the Expert – Using Disease Models at the Air Liquid Interface to Advance Respiratory Disease Studies
Learn More: Ask the Expert – Using Disease Models at the Air Liquid Interface to Advance Respiratory Disease StudiesWith the popularity of these more complex models growing, we have assembled a team of experts to answer your questions on disease modeling using ALI tools and systems.
Tissue Engineering: The Latest 3D Cellular Models for Respiratory Drug Development
Learn More: Tissue Engineering: The Latest 3D Cellular Models for Respiratory Drug DevelopmentLearn how a company in Switzerland is harnessing the latest cell culture technology to build even more predictive 3D cellular models for respiratory disease research.
Uses and Best Practices for Air-liquid Interface
Learn More: Uses and Best Practices for Air-liquid InterfaceLearn more about the tools, uses and techniques for air-liquid interface cultures.
ALI Culture Research
Learn More: ALI Culture ResearchAir-liquid interface (ALI) cell cultures could play a growing role in the lab. Here’s what you need to know to get started.
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技术支持——设定新的行业标准
技术支持——设定新的行业标准
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我们致力于确保您成功完成细胞培养，而且在成交之后我们仍会继续提供优质服务。康宁专家团队会不断完善我们的工具，推动您探索新发现，随时为您研究的每一步提供鼎力支持。需要我们帮助您选择合适的表面？正在处理复杂的细胞？需要定制功能？通过建立合作伙伴关系，康宁可以帮助您解决各种具体难题。随时随地满足所需——康宁是值得您完全信赖的合作伙伴，可确保您选择适当的实验室研发工具。
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