PureCoat ECM Mimetic Cultureware

Support your clinical research with the scientifically defined, natural performance of Corning®

PureCoat ECM mimetic

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Enhance cell culture performance with our next-generation family of chemically defined, animal-free PureCoat surfaces. A proprietary thin-film coating technology produces a uniform, functionalized surface that provides a highly controlled environment for cell culture applications, improving the culturing of animal-free, defined cells without compromising performance.

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Choice

Create a fully defined cell culture environment—serum-, xeno-, or animal-free

Create a fully defined cell culture environment

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Support the growth of stem and primary cells across a broad range of defined media formulations with the choice of two ECM mimetic types:

PureCoat ECM mimetic fibronectin peptide consists of RGD sequences to support the attachment of cell types that require fibronectic coating, such as alpha-5 integrin-positive cells.

PureCoat ECM mimetic collagen I peptide supports the attachment of collagen I-dependent cell types, including alpha 2 integrin-positive cells, among others.

Support the growth of stem and primary cells across a broad range of defined media formulations with the choice of two ECM mimetic types:

PureCoat ECM mimetic fibronectin peptide consists of RGD sequences to support the attachment of cell types that require fibronectic coating, such as alpha-5 integrin-positive cells. This fibronectic peptide is a compatible, animal-free alternative to natural animal or human ECM surfaces, such as natural human fibronectin for hMSC expansion and differentiation.

PureCoat ECM mimetic collagen I peptide supports the attachment of collagen I-dependent cell types, including alpha 2 integrin-positive cells, among others. It provides a compatible, animal-free alternative to natural animal or human ECM surfaces, such as natural human collagen I for human keratinocytes expansion

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Cells

PureCoat ECM mimetic cultureware enables cell growth in a board range of cell types.

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Corning PureCoat ECM Mimetic Type

Known Compatible Cell Types Expanded in Defined Cell Culture Environments

Fibronectin Peptide

Human BM-derived Mesenchymal Stem Cells

Human Endothelial Progenitor Cells

Human Adipose-derived Stem Cells

Human Lung Stromal Cells

CHO Cells

Vero Cells

Collage I Peptide

Human Keratinocytes

Human Corneal Cells

Human Adipose-derived Stem Cells

Human Endothelial Progenitor Cells

Human Cord Blood-derived Mesenchymal Stem Cells (isolation)

Vero Cells

Features

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Animal component-free, synthetic peptide coating covalently attached to cultureware
Manufactured in compliance with cGMP and certified to ISO 9001 and ISO 13485
Compatible with a wide range of serum-free, xeno-free, and animal-free media formulations
Sterile, SAL10^-3, nonpyrogenic and non-cytotoxic
Quality control tested using an appropriate cell attachment assay
Room temperature stable 18 months from date of manufacture
Raw materials tested and meets USP Class VI requirements
Compatible with a broad range of cell dissociation reagents
Lot traceable; certificate of compliance available upon request

Animal component-free, synthetic peptide coating covalently attached to cultureware
Manufactured in compliance with cGMP and certified to ISO 9001 and ISO 13485
Compatible with a wide range of serum-free, xeno-free, and animal-free media formulations
Sterile, SAL10^-3, nonpyrogenic and non-cytotoxic
Quality control tested using an appropriate cell attachment assay
Room temperature stable 18 months from date of manufacture
Raw materials tested and meets USP Class VI requirements
Compatible with a broad range of cell dissociation reagents
Lot traceable; certificate of compliance available upon request

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Benefits

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Enables a fully defined cell culture for a reproducible environment which supports predictable expansion and differentiation
Pre-coated and ready to use at room temperature, minimizing risk of experimental failure due to inconsistent ECM self-coating, and risk of pre-coated biological performance failure due to incorrect storage
cGMP-compliant manufacturing and animal-free traceability, mitigating variability and risk of contamination
Simplified supply chain requirements, with no need for costly cold chain transport and storage
Scalable formats to meet a wide range of cell expansion needs to suit any stage of research

Enables a fully defined cell culture for a reproducible environment which supports predictable expansion and differentiation
Pre-coated and ready to use at room temperature, minimizing risk of experimental failure due to inconsistent ECM self-coating, and risk of pre-coated biological performance failure due to incorrect storage
cGMP-compliant manufacturing and animal-free traceability, mitigating variability and risk of contamination
Simplified supply chain requirements, with no need for costly cold chain transport and storage
Scalable formats to meet a wide range of cell expansion needs to suit any stage of research

Learn More

Applications and Use

PureCoat in Action

Human Mesenchymal Stem Cells

Mesenchymal Stem Cells

Expand and differentiate hMSCs in defined serum-free, xeno-free, or animal-free

Human Keratinocytes

Choose PureCoat Collagen I peptide surface, an animal-free alternative to animal

Endothelial Progenitor Cells

For research in regenerative medicine, successfully culture EPCs on PureCoat

Mammalian Cell Types

Enhance attachment and proliferation of Vero and CHO-K1 cells using PureCoat

Stem Cell Research

Corning has been committed to stem cell research for decades, developing the necessary tools that allow you to advance groundbreaking research in the field.

Webinar: PureCoat ECM Mimetic Cultureware

Growing concerns about introducing human- and animal-derived pathogens into cell culture necessitate the need for animal-free cell culture environments. Learn how PureCoat ECM mimetic cultureware presents a defined, synthetic surface for cell culture without compromising performance.

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