Matrigel Matrix-3D Plates | Extracellular Matrix Pre-coated Plates

Support consistent and robust growth of 3D cell cultures with Corning Matrigel Matrix-3D Plates

Convenience. Consistency. Certainty. That is what you can expect from new Corning Matrigel matrix-3D plates.

Corning Matrigel matrix, a natural extracellular matrix (ECM)-based hydrogel, is widely used and referenced in 3D cell culture, in support of organoid and spheroid formation. As 3D cell culture models migrate into a high throughput environment, the need for more convenient, consistent, pre-coated format options has emerged.

Corning is pleased to offer our new Matrigel matrix-3D plates, a pre-coated, ready-to-use option available in 96-well and 384-well formats. Matrigel matrix is pre-dispensed into each well to support both spheroid and organoid models in a high throughput environment where ‘on-top/sandwich’ and ‘embedded’ workflows are desired to generate 3D cell cultures.

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Learn More About Matrigel Matrix-3D Plates

Convenient

The Matrigel matrix-3D plates reduce workflow steps for the researcher and eliminates the need to handle small volume ECM dispensation. This convenient, off-the-shelf option helps researchers improve productivity in homogenous assays where 3D structures are grown and assayed directly in the plate.

Consistent

Corning has built-in quality control to ensure a consistent volume of Matrigel matrix is dispensed into each well. In fact, Z’ values of high throughput assays conducted using Matrigel matrix-3D plates demonstrate a robust assay and consistent plate-to-plate performance¹.

Matrigel matrix-3D plates reduce the manual inaccuracies of self-coating and gives researchers the convenience of a “plug and play” protocol to grow and assay 3D structures directly in the plate.

Certain

Corning Matrigel matrix-3D plates have been shown to:

Support formation of 3D polarized epithelial structures¹ and cancer spheroids
Successfully support screening with drug compound libraries
Provide a suitable format for drug discovery research on pancreatic, ovarian, prostate, and intestinal organoids (as reported by customers)

Corning Matrigel matrix-3D plates have been shown to:

Support formation of 3D polarized epithelial structures¹ and cancer spheroids
Successfully support screening with drug compound libraries
Provide a suitable format for drug discovery research on pancreatic, ovarian, prostate, and intestinal organoids (as reported by customers)

References

1. Corning Matrigel Matrix-3D Plates for High Throughput 3D Assays (Corning Lit. Code CLS-AN-572)

Supporting Data

Discover how Matrigel matrix-3D plates can be used for organoids, cancer spheroids, and tumoroids for drug discovery, drug screening, and personalized medicine

Polarized Epithelial 3D Structures

Polarized Epithelial 3D Structures

Support Growth of Polarized Epithelial 3D Structures.¹ Read our application note to learn more.

Cancer Spheroids

Cancer Spheroids

Support Growth of Cancer Spheroids. Read our sell sheet to learn more.

Screening with Drug Compounds

Screening with Drug Compounds

Support Screening with Drug Compound Libraries.¹ Read our application note to learn more.

References

1. Corning Matrigel Matrix-3D Plates for High Throughput 3D Assays (Corning Lit. Code CLS-AN-572)

Resources

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